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Solicitation

UNifying Imaging with QUantum Entanglement (UNIQUE) Innovative Solutions Opening (ISO)

ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

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Response status

Due in 37 days

Dec 16, 2026, 4:59 AM UTC

Responses remain open.

Posted
Sep 24, 2026
Archive date
Feb 15, 2027
SAM status
Active

Answer-first brief

What the source record says

  • ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) published this solicitation.
  • Competition is listed as No Set aside used.
  • The notice uses NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)).

Procurement identity

Notice ID
b656f68a72844aa6b6013ad9295625c7
Solicitation
ARPA-H-SOL-26-162
Base type
Solicitation
Version
1 of 1

Solicitation facts

Structured fields from the current SAM notice version. A dash means the source did not publish a value.

Notice type
Solicitation
Solicitation number
ARPA-H-SOL-26-162
NAICS
541714 — Research and Development in Biotechnology (except Nanobiotechnology)
PSC
AN13 — HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
Set-aside
No Set aside used
Set-aside code
—
Posted
Sep 24, 2026
Responses due
Dec 16, 2026, 4:59 AM UTC
Archive date
Feb 15, 2027
Archive type
autocustom
Base type
Solicitation
Organization type
OFFICE
Benchmark category
—
Category confidence
—
Category source
—
Last seen
Oct 21, 2026

Buyer and place

Office hierarchy and place of performance as published.

Department
HEALTH AND HUMAN SERVICES, DEPARTMENT OF
Department code
—
Subagency
National Institutes of Health
Subagency code
—
Office
ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)
Organization path
—
Organization path codes
—
Office address
Washington, DC, 20005, USA
Place of performance
—
City code
—
State
—
State code
—
Postal code
—
Country
—

Points of contact

Contact details from the current notice version.

Notice description

Source text reproduced without an AI summary.

Amendment 01: The Proposers' Day has been updated to October 16th, 2026. The Advanced Research Projects Agency for Health (ARPA-H) is posting this Innovative Solutions Opening (ISO) in support of the UNifying Imaging with QUantum Entanglement (UNIQUE) Program. ARPA-H anticipates that multiple Other Transaction (OT) Agreements will result from this announcement. Interested parties are invited to review the attached UNIQUE-ISO-ARPA-H-SOL-26-162 and UNIQUE ISO Attachments. Additionally, proposers are encouraged to review the separate Special Notice, ARPA-H-SN-26-162, for information regarding the UNIQUE Proposers� Day. Special Notice, ARPA-H-SN-26-162, is an independent announcement and is not attached to this ISO announcement. All questions submitted to the ISO will be compiled and addressed. All answers will be posted to the UNIQUE Frequently Asked Questions (FAQ) page. Potential proposers are encouraged to monitor the FAQs page regularly for the latest information and updates: https://arpa-h.gov/explore-funding/programs/unique/faqs

Comparable award range

Historical award values for work matched by the fixed rubric—not an estimate of this opportunity.

Low end (p25)$600,000
Median$4,053,920
High end (p75)$15,342,585
Comparable awards
50
Median
$4,053,920
Computed
Nov 5, 2026
Rubric
comparables@2026.08.1
Comparable award values describe completed contracts. They do not state the government's budget and are not a bid recommendation.

Comparable awards

The match score is decomposed so each comparison can be challenged.

AwardContractorValueAwardedScoreWhy it matched
TOPIC 5 SBIRMEMSEL INC.$593,800.00Feb 26, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
CELL AND GENE THERAPY PROCESS ANALYTICAL TECHNOLOGY AND QUALITY CONTROL TESTINGQUANTITATIVE BIOSCIENCES, INC.$600,000.00Apr 6, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
CELL AND GENE THERAPY PROCESS ANALYTICAL TECHNOLOGY AND QUALITY CONTROL TESTINGHELIOWAVE TECHNOLOGIES INC$600,000.00Apr 6, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
PHYSICAL SCIENCES INC. (PSI) AIMS TO DEVELOP AND COMMERCIALIZE A FIRST-OF-ITS-KIND IN-LINEPHYSICAL SCIENCES INC.$3,499,995.99Feb 26, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
SBIR PH II "TRANSLATION OF NOVEL BILIARY TRACT-SPECIFIC CONTRAST AGENT TO MEDIATE SUCCESSFOPTOSURGICAL, LLC$2,095,748.00Apr 8, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
C02 SENSOR PROTOTYPE DEVELOPMENTRED DUKE STRATEGIES LLC$1,499,888.00Sep 23, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
TCR SEQUENCINGCD BIOSCIENCES INC$45,200.00Apr 14, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
HISTOLOGICAL ANALYSIS OF H9VIRSCIO, INC$185,908.00Jun 5, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
DEOBLIGATE AND CLOSE OUT THE CONTRACT CLIN 0005 OPTION 4 DECREASED BY $216,710.73 CLIN 000SPERO THERAPEUTICS, INC.$49,196,133.50Jul 6, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
EOI::PRESIDENTIAL COST SAVINGS INITIATIVE (FEBRUARY 26, 2025):EOI MODIFICATION TO TRANSMITMEDIWOUND LTD$4,384,812.00Mar 13, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
THE PURPOSE OF THIS BILATERAL MODIFICATION DE-OBLIGATES CANCELING YEAR FUNDS FROM REQUISITVENATORX PHARMACEUTICALS INC$131,756,813.69May 26, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
THE PURPOSE OF THIS MODIFICATION IS TO EXERCISE OPTION 6.PUBLIC HEALTH VACCINES LLC$89,026,882.76Jun 8, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
A RAPID, ACCURATE, POC DISPOSABLE INFLUENZA AND SARS-COV-2 MOLECULAR DIAGNOSTICVISBY MEDICAL, INC.$41,169,014.00Mar 26, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
HIGH THROUGHPUT SARS-COV-2 NEUTRALIZING ANTIBODY IMMUNOASSAY FOR QUALIFYING VARIANTS AND TMONOGRAM BIOSCIENCES, INC.$38,008,678.50Mar 4, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
THE OVERALL OBJECTIVE OF THIS CONTRACT IS TO DEVELOP AND COMMERCIALIZE A RAPID PHENOTYPIC BECKMAN COULTER, INC$36,655,675.00Mar 27, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
THE PURPOSE OF THIS MODIFICATION IS TO EXTEND CLIN0001/BASE THROUGH DECEMBER 31, 2026, PROENALARE THERAPEUTICS INC$12,209,278.00May 18, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
ADD CLIN 0014 AND FUND $6,500,205.00, REVISE CLINS POP FOR STANDARDIZATION TO DECEMBER 27,GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC.$70,479,398.00Jun 8, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
THE PURPOSE OF THIS MODIFICATION IS TO UPDATE THE PERIOD OF PERFORMANCE END DATE FROM AUGUCASTLEVAX INC$8,294,985.00Mar 27, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
RADNUC 2201: PERFORMANCE VERIFICATION OF INSTITUTIONAL RADIATION DOSE RESPONSE FOR ACUTE RLOVELACE BIOMEDICAL RESEARCH INSTITUTE$5,905,018.00Mar 3, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)
BIO-AMT-2301: IDIQ CONTRACT MANAGEMENT SUPPORT ACTIVITIESMRIGLOBAL$149,664.00Jul 17, 202652Same product and service code (25), Same industry code (20), Recent enough to be relevant (7)

Record provenance

Field-level lineage for the current opportunity version.

FieldSourceSource as ofParserTransform
agency_nameSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
archive_dateSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
archive_typeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
base_typeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
contactsSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
descriptionSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
naics_codeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
notice_idSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
notice_typeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
office_citySAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
office_country_codeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
office_nameSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
office_postal_codeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
office_state_codeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
organization_typeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
posted_dateSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
psc_codeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
response_deadlineSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
sam_urlSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
set_aside_label_rawSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
solicitation_numberSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
subagency_nameSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
titleSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3
upstream_activeSAM.gov Contract OpportunitiesSep 26, 2026sam_opportunity_snapshot@2026.08.32026.08.3

Sources and method

Figures on this page are computed from public federal award records. Numbers are never estimated or generated; where a figure is withheld, the reason is stated rather than filled in.

Comparable awards are scored on benchmark category, product and service code, industry code, buyer, place, recency, and contract type. Rubric version comparables@2026.08.1.

  1. 1Notice fields come from the SAM.gov contract opportunities record last seen Oct 21, 2026. SAM.gov remains authoritative.
  2. 2Computed from 50 completed federal awards using comparables@2026.08.1, as of Nov 5, 2026. Award values are neither unit prices nor a forecast.

Note 1 covers the solicitation record; note 2 covers the comparable range. No synthetic FAQ or inferred solicitation value is published.